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<A HREF="http://neuroseries.info.nih.gov">NIH Neuroscience Seminar Series</A> <br><br> A master circadian clock resides in the suprachiasmatic nuclei (SCN) of the anterior hypothalamus of mammals. Recent discoveries in this and other laboratories have identified a molecular framework for the core clock mechanism in the SCN. The core mechanism involves interacting positive and negative transcriptional/post-translational feedback loops. <br><br> For more information, visit <br> <A HREF="http://www.umassmed.edu/neuroscience/faculty/reppert.cfm">Steven Reppert</A><br>